Alex M Clark

From Scientistsdb

Alex M. Clark
Born	29 July 1974 Auckland, New Zealand
Residence	Montréal, Canada
Nationality	New Zealand + Canadian
Fields	cheminformatics, structure based drug discovery, organometallics
Institutions	Molecular Materials Informatics, Inc.
Alma mater	University of Auckland
Doctoral advisor	W.R. Roper, L.J. Wright

Overview

Dr. Alex M. Clark is the founder of Molecular Materials Informatics, Inc. which produces a number of mobile chemistry apps, including the Mobile Molecular DataSheet.

Born, raised and educated in New Zealand, relocated to North America just prior to the new millenium, and now lives in Montréal, Canada.

History

• 2010 - now: Founder, Molecular Materials Informatics, Inc.
• 2004 - 2010: Research Scientist, Chemical Computing Group Inc., Montréal, Canada
• 2001 - 2003: Computational Scientist, IntelliChem Inc., Oregon, USA (now Symyx/Accelrys)
• 1999 - 2001: PostDoctoral Fellow: Fullerene Chemistry, University of California, Riverside, USA
• 1997 - 1999: Ph.D.: Organometallic Chemistry, University of Auckland, New Zealand
• 1995 - 1997: M.Sc.: Inorganic/Organometallic Chemistry, University of Auckland, New Zealand
• 1992 - 1994: B.Sc.: Chemistry, Computer Science; University of Auckland, New Zealand

Publications

• Open Drug Discovery Teams: A Chemistry Mobile App for Collaboration, S. Ekins, A.M. Clark, A.J. Williams, Molecular Informatics, 31, 585-597 (2012)
• Redefining Cheminformatics with Intuitive Collaborative Mobile Apps, A.M. Clark, S. Ekins, A.J. Williams, Molecular Informatics, 31, 569-584 (2012)
• Mobile apps for chemistry in the world of drug discovery, A.J. Williams, S. Ekins, A.M. Clark, J.J. Jack, R.L. Apodaca, Drug Discovery Today, 16, 928-939 (2011).
• Accurate Specification of Molecular Structures: The Case for Zero-Order Bonds and Explicit Hydrogen Counting, A.M. Clark, Journal of Chemical Information and Modeling, 52, 3149-3157 (2011).
• 2D Depiction of Fragment Hierarchies, A.M. Clark, Journal of Chemical Information and Modeling, 50, 37-46 (2010)
• Basic primitives for molecular diagram sketching, A.M. Clark, Journal of Cheminformatics, 2:8 (2010).
• Detection and Assignment of Common Scaffolds in Project Databases of Lead Molecules. A.M. Clark, P. Labute, Journal of Medicinal Chemistry, 52, 469-483 (2009).
• 2D Depiction of Protein−Ligand Complexes. A.M. Clark, P. Labute, Journal of Chemical Information and Modeling, 47, 1933-1944 (2007).
• Flexible 3D pharmacophores as descriptors of dynamic biological space. J.H. Nettles, J.L. Jenkins, C. Williams, A.M. Clark, A. Bender, Z. Deng, J.W. Davies, M. Glick, Journal of Molecular Graphics and Modelling, 26, 622-633 (2007).
• 2D Structure Depiction. A.M. Clark, P. Labute, M. Santavy, Journal of Chemical Information and Modeling, 46, 1107-1123 (2006).
• Bis(N,N'-dimethylimidazol-2-ylidene)mercury chlorotriiodomercury dimethyl sulfoxide solvate. A.M. Clark, C.E.F. Rickard, A.G. Oliver, L.J. Wright, W.R. Roper, Acta Crystallographica, C56, 26 (2000)
• Bromination and nitration reactions of metallated (Ru and Os) multiaromatic ligands and crystal structures of selected products. A.M. Clark, C.E.F. Rickard, W.R. Roper, L.J. Wright, Journal of Organometallic Chemistry, 598, 262 (2000)
• Stepwise Conversion of an Osmium Trimethylstannyl Complex to a Triiodostannyl Complex and Nucleophilic Substitution Reactions at the Tin-iodine Bonds. A.M. Clark, C.E.F. Rickard, T.J. Woodman, L.J. Wright, W.R. Roper, Organometallics, 19, 1766 (2000)
• The origin of the 'spike' in the EPR spectrum of C60-. P. Paul, R.D. Bolskar, A.M. Clark, C.A. Reed, Chemical Communications, 1229 (2000)
• Cyclometallated complexes of ruthenium and osmium containing the o-C6H4PPh2 ligand. M.A. Bennett, A.M. Clark, M. Contel, C.E.F. Rickard, W.R. Roper, L.J. Wright, Journal of Organometallic Chemistry, 601, 299 (2000)
• Ph.D. Thesis: Aryl Organometallic Compounds of Ruthenium and Osmium
• Electrophilic Aromatic Substitution Reactions at the Phenyl Ring of the Chelated 2-(2'-Pyridyl)phenyl) Ligand Bound to Ruthenium(II) or Osmium(II). A.M. Clark, C.E.F. Rickard, W.R. Roper, L.J. Wright, Organometallics, 18, 2813 (1999)
• 5-Bromination of an η2-8-Quinolyl Ligand Bound to Osmium(II) and Subsequent Lithiation and Derivatization of This Functionalized Ligand. A.M. Clark, C.E.F. Rickard, W.R. Roper, L.J. Wright, Organometallics, 17, 4535 (1998)
• Osmium complexes containing either chelating or non-chelating 8-quinolyl ligands. A.M. Clark, C.E.F. Rickard, W.R. Roper, L.J. Wright, Journal of Organometallic Chemistry, 545-546, 619 (1997)
• M.Sc. Thesis: Synthetic Approaches to Ruthenium and Osmium Stannyl Complexes
• Osmium nitrosyl complexes with osmium-tin bonds; Crystal structure of Os[Sn(p-tolyl)3](NO)(CO)2(PPh3). A.M. Clark, C.E.F. Rickard, W.R. Roper, L.J. Wright, Journal of Organometallic Chemistry, 543, 111 (1996)

Contact Details

Alex Michael Clark

Email: aclark@molmatinf.com

Social Network Links

Company: Molecular Materials Informatics, Inc.

Blog: Cheminformatics 2.0

Twitter: @aclarkxyz

LinkedIn: dralexmclark

Google Scholar: citations

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